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Welcome to the Madhukar
Group!
We
are an inter-disciplinary group of curious people exploring
the synthesis, properties, and applications of novel
quantum nanostructures (wells, wires, & dots). Our
current focus is on (1) a new paradigm that we proposed
for solar energy conversion utilizing integrated hybrid
quantum dot and nanowire systems, (2) synthesis and
properties of new and novel nanostructures that arise
from the integration of highly dissimilar materials
hitherto unexplored, (3) nano-scale spatially-resolved
optical imaging of multiple biomarker expression in
live cells under controlled external stress (mechanical,
electrical, chemical) over prolonged periods of time
(days) to understand intra-cellular signalling pathways
in the apoptosis of neuronal cells, and (4) the use
of the tools of nanoscience and specially designed and
synthesized functional active nanosystems for probing,
manipulating, and potentially endowing new functions
in live cells.
We utilize a suite of synthesis
techniques (ranging from cutting-edge vapor phase to
solution chemistry based), structural examination (high-resolution
transmission electron microscopy, ex-situ and in-situ
atomic force and scanning tunneling microscopies, etc.),
optical examination (photoluminescence, UV-visible fluorescence,
Raman, spectroscopic ellipsometry, Fourier transform
infrared spectroscopy, time resolved spectroscopy),
and electrical and opto-electronic (photocurrent) characterization.
For the biochemical and biological aspects of our work
we have state-of-the-art cell and molecular biology
facilities (see Labs&Facilities)
and employ the usual range of techniques along with
two unique experimental stations: (a) a combined atomic
force microscope and near-field scanning optical microscope
that utilizes a cantilever made of optical fiber, and
(b) an optical imaging system that, unlike typical optical
microscope systems, allows
time-multiplexed imaging of morphology and multiple
biomarkers in large numbers (30-50) of live cells in
a population under controlled external stress over prolonged
time (days).
We are constantly on the look
out for "a few good students". If you have a
strong undergraduate degree in science (including biochemistry
and chemical biology) or engineering (including bio-
and biomedical engineering), are self-driven, communicative,
committed to PhD, enjoy good food and conversation,
and your passion to learn greater than fear of walking
unknown territory, then contact
us. We are the place for you!
Major
interdisciplinary projects
involving multi-faculty/institution collaboration are
funded by the DURINT
(Defense Universtiy Research Initiative in Nanotechnology)
program of the NNI
(National nanotechnology Initiative), MURI ( Multidisciplinary
University Research Initiative), and the BMES
ERC (Biomimetic MicroElectronic Systems Engineering
Research Center) program of the NSF
(National Science Foundation).
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